2025 Year in Review: The Year We Became Real

USD Discovery District logo over title, "2025 Year in Review" over dark red gradient image of Building 1

In 2025, the USD Discovery District shifted from development to destination. With Building 1 activated, new tenants moving in, national leaders visiting Sioux Falls, and global partnerships taking shape, the District’s momentum became impossible to ignore.

New 2025 Market Study Shows South Dakota Poised for Significant Bioscience Growth

University of South Dakota Discovery District brand logo on red field.

The USD Discovery District has released the 2025 Market Study, a data driven look at South Dakota’s bioscience strengths, cost and speed advantages, talent pathways, and alignment with national research priorities including the recently announced Genesis Mission. Explore how the state is positioning itself for the next decade of bioscience growth.

Building the Future, One Connection at a Time

Attendees network inside the modern lobby of the USD Discovery District during the grand opening event.

President Ryan Oines shares how the USD Discovery District’s new website reflects a digital milestone, built to connect partners, highlight progress, and grow South Dakota’s bioscience ecosystem.

What Are Communities of Innovation — and Why They Matter for the Midwest

Kenosha Innovation Center ribbon cutting event celebrates a new addition to the Kenosha, WI neighborhood.

Across the Midwest, cities are re-imagining how people, ideas, and industries connect. Communities of innovation—also called research parks or innovation districts—bring together universities, private companies, and civic leaders to accelerate discovery, entrepreneurship, and job creation. These districts are redefining what economic development looks like. Rather than isolated R&D centers, they build entire ecosystems where researchers, […]

The USD Discovery District is Ready for Innovators

USD Discovery District team welcomes the City of Sioux Falls to tour the new construction of Building 1 in Sioux Falls, SD.

In the heart of northwestern Sioux Falls, a significant milestone has been achieved with the opening of the first building in the USD Discovery District, marking a palpable step towards transforming this area into a hub for innovation, particularly in the life sciences and biotechnology sectors. The journey to this point has been neither swift […]

USD Discovery District announces first tenants as building prepares to start

USD Discovery District presents to the South Dakota Board of Regents meeting in 2024.

Published by Siouxfalls.business on December 14, 2023. This paid piece is sponsored by South Dakota Biotech. The first tenants have been secured, and construction is starting for the first building at the USD Discovery District. The two-story office and research building at 4600 W. Nobel St. came in 13 percent under the initial cost estimate, […]

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