Opened in January 2025, Building 1 at the USD Discovery District is a 50,000-square-foot beacon of innovation in Sioux Falls, South Dakota. As the first building of the 80-acre research park, this state-of-the-art facility offers customizable lab and office spaces designed for biotech and life sciences pioneers. Home to tenants like OmegaQuant Analytics, Building 1 fosters collaboration among industry, academia, and government, driving breakthroughs that shape the future. Whether you need a lab and office combo or a fully built research lab, Building 1 has the infrastructure and location you need to thrive.
37,924 leasable square feet, including build-to-suit labs and cGMP-compliant suites for research and manufacturing, tailored to stringent biotech needs.
Located near USD’s Sioux Falls campus and the GEAR Center, enabling partnerships with researchers, students, and healthcare leaders like Sanford and Avera Health.
Access conference rooms, prototyping facilities, and university services to accelerate development and commercialization.
Completed 13% under budget by ISG and McGough Construction, Building 1 blends efficiency with cutting-edge functionality, supporting long-term growth.
Funded by $25 million, including $15 million from the South Dakota Legislature and $4 million from Sioux Falls, Building 1 is a cornerstone of a research park projected to generate 2,800 jobs and $314 million in economic impact. Designed by ISG, a leader in collaborative architecture, the two-story facility integrates private sector innovation with student workforce and research tools. Its strategic location west of the USD classroom building ensures accessibility while leaving space for future campus growth. Building 1 is more than a building—it’s a launchpad for South Dakota’s biotech revolution.
Common Spaces include conference room, restrooms (with showers), mail room and break room.
Available spaces include six offices in our co-working center and up to 6,000 leasable square footage.
Common Spaces include conference room, restroom (with showers), and wellness room.
Available spaces are up to 15,000 square footage.
Looking for biotech lab space in Sioux Falls? With 37,924 leasable square feet, Building 1 is South Dakota’s most advanced life sciences facility.
4600 West Nobel Street, Suite 102
Sioux Falls, SD 57107
605.275.8010
info@usddiscovery.com